For a long time, the Visual Studio debugger allowed to debug both backend .NET code and client-side JavaScript running in the browser. Unfortunately the only browser were this was supported was Internet Explorer.
With the upcoming release of Visual Studio 2017, this will finally change. From now on you can debug your JavaScript and TypeScript running in Chrome from inside Visual Studio.
You only need to select Chrome as your browser inside Visual Studio, hit F5 and a debugger will be attached.
Great feature!
More information: https://blogs.msdn.microsoft.com/webdev/2016/11/21/client-side-debugging-of-asp-net-projects-in-google-chrome/