.NET 6 introduces a new way to write your API’s without the need of a Startup.cs file. More about ‘Minimal APIs’ as this feature is called can be found here: https://docs.microsoft.com/en-us/aspnet/core/tutorials/min-web-api?view=aspnetcore-6.0 https://docs.microsoft.com/en-us/aspnet/core/fundamentals/minimal-apis?view=aspnetcore-6.0 But how do you write an integration test for such a minimal API? Before you used the WebApplicationFactory<TStartup> and specified the Startup.cs as the generic argument of the factory. But now the Startup.cs file is gone. Luckily Microsoft thought about this and updated the Microsoft.AspNet.Mvc.Testing package to work without it. I find the solution not very clean but at least it works. Here are the steps you need to take: Microsoft made it possible to use the Program.cs file as the generic argument instead of the Startup.cs file. Unfortunately by default the Program.cs file is internal so we have to make some chang...